S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Chl1p
Description	Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity and interstrand cross-link repair; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome
GO Terms: Biological Process	level 3: establishment of sister chromatid cohesion level 4: mitotic sister chromatid cohesion level 5: mitotic G1 DNA damage checkpoint signaling level 6: interstrand cross-link repair
GO Terms: Molecular Function	level 2: nucleic acid binding level 2: helicase activity level 2: ATP hydrolysis activity level 3: DNA binding level 3: DNA helicase activity level 4: 5'-3' DNA helicase activity level 4: ATP binding level 4: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO Terms: Cellular Component	level 2: chromatin level 4: nucleus
External source	Open in SGD