S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rox1p
Description	Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance
GO Terms: Biological Process	level 3: cell differentiation level 4: cellular response to osmotic stress level 5: cellular response to increased oxygen levels level 5: cellular response to salt stress level 10: negative regulation of transcription by RNA polymerase II level 10: positive regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 2: DNA-binding transcription factor activity level 3: transcription corepressor activity level 4: sequence-specific DNA binding level 4: DNA-binding transcription repressor activity, RNA polymerase II-specific level 4: DNA-binding transcription activator activity, RNA polymerase II-specific level 4: double-stranded DNA binding level 4: DNA binding, bending level 5: cis-regulatory region sequence-specific DNA binding level 6: RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO Terms: Cellular Component	level 2: chromatin level 4: nucleus
External source	Open in SGD