S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Taz1p
Description	Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant
GO Terms: Biological Process	level 5: phospholipid metabolic process level 5: phospholipid biosynthetic process level 6: inner mitochondrial membrane organization level 6: ATP synthesis coupled electron transport level 6: mitochondrial respirasome assembly level 8: cardiolipin metabolic process level 9: cardiolipin acyl-chain remodeling
GO Terms: Molecular Function	level 3: acyltransferase activity level 5: 1-acylglycerophosphocholine O-acyltransferase activity
GO Terms: Cellular Component	level 3: mitochondrion level 4: mitochondrial membrane level 4: mitochondrial outer membrane level 4: mitochondrial inner membrane
External source	Open in SGD