S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tif3p
Description	Translation initiation factor eIF-4B; RNA recognition motif containing single-stranded RNA binding protein that possesses RNA annealing and strand-exchange activities; stimulates the ATPase and unwinding activities of the RNA helicase eIF4A, in a synergistic manner with eIF4G; promotes assembly of the translation initiation factor complex eIF4F and the 48S preinitiation complex; interacts with Rps20p at the head of the 40S ribosomal subunit and alters the structure of the mRNA entry channel
GO Terms: Biological Process	level 3: translational initiation level 5: formation of translation preinitiation complex level 6: cytoplasmic translation level 6: eukaryotic translation initiation factor 4F complex assembly
GO Terms: Molecular Function	level 2: nucleic acid binding level 3: RNA binding level 4: RNA strand annealing activity level 4: single-stranded RNA binding level 4: mRNA binding level 5: RNA strand-exchange activity level 5: ribosomal small subunit binding
GO Terms: Cellular Component	level 4: nucleus level 4: nucleolus level 4: cytoplasmic stress granule
External source	Open in SGD