Yeastract
YEASTRACT+
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Modelling prediction
Fitness-linked TFs (quant.)
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Vps4p
Description
AAA-ATPase involved in multivesicular body (MVB) protein sorting; ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism
GO Terms:
Biological Process
level 3:
endosomal transport
level 3:
late endosome to vacuole transport
level 4:
intralumenal vesicle formation
level 4:
macroautophagy
level 4:
late endosome to vacuole transport via multivesicular body sorting pathway
level 4:
protein retention in Golgi apparatus
level 5:
vacuole organization
level 5:
reticulophagy
level 5:
membrane fission
level 6:
sterol metabolic process
level 8:
double-strand break repair via break-induced replication
level 8:
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO Terms:
Molecular Function
level 2:
ATP hydrolysis activity
level 4:
ATP binding
GO Terms:
Cellular Component
level 2:
membrane
level 2:
cytoplasm
level 3:
endosome
level 3:
endoplasmic reticulum
level 4:
endosome membrane
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