Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SSL2 Systematic Name
YIL143C Alias
LOM3, RAD25 Strain
S288c Description
Component of RNA polymerase transcription factor TFIIH holoenzyme; acts as dsDNA-dependent translocase in context of TFIIH, unwinds DNA strands during initiation and promotes transcription start site (TSS) scanning; has DNA-dependent ATPase/helicase activity; interacts functionally with TFIIB, has roles in TSS selection and gene looping to juxtapose initiation and termination regions; involved in DNA repair; relocalizes to cytosol under hypoxia; homolog of human ERCC3 External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>SSL2 YIL143C
ATGACGGACGTTGAAGGCTACCAACCTAAGAGCAAGGGGAAAATCTTTCCAGATATGGGT
GAGTCCTTTTTCTCATCAGATGAGGATTCACCAGCTACTGATGCAGAGATCGATGAGAAC
TATGATGATAACAGGGAAACGTCAGAAGGACGTGGAGAAAGGGATACCGGCGCCATGGTA
ACAGGGTTGAAGAAGCCTCGGAAAAAGACCAAGAGTAGCAGGCATACAGCGGCGGATTCC
TCTATGAATCAAATGGACGCTAAGGATAAAGCGCTTTTGCAGGACACTAATAGCGATATA
CCAGCAGATTTCGTTCCAGATTCCGTCTCTGGAATGTTCAGAAGCCATGACTTTAGTTAT
TTGCGGTTAAGACCAGACCATGCTTCCAGGCCCCTTTGGATCTCGCCAAGTGACGGTAGG
ATCATTCTGGAGAGTTTCTCTCCATTAGCAGAACAGGCTCAGGACTTTCTGGTCACCATT
GCAGAGCCTATAAGTAGACCCTCCCATATTCATGAATACAAGATCACAGCATACTCTTTG
TATGCAGCTGTTTCTGTAGGGTTGGAGACGGATGATATCATTTCAGTTCTGGATAGATTA
TCCAAAGTACCCGTTGCTGAATCGATAATCAACTTCATTAAAGGGGCTACCATTTCATAC
GGTAAAGTGAAACTAGTTATTAAGCATAATAGATATTTCGTGGAGACTACACAAGCAGAT
ATTCTGCAAATGTTGCTGAATGATTCCGTCATCGGGCCCCTAAGAATAGATAGCGATCAT
CAAGTACAGCCACCAGAGGATGTACTACAGCAACAACTTCAGCAAACCGCTGGAAAACCC
GCTACTAATGTTAATCCGAACGATGTGGAAGCCGTGTTTAGTGCAGTTATAGGTGGTGAT
AATGAGCGGGAAGAAGAAGATGATGATATTGATGCCGTTCACTCCTTTGAAATTGCCAAT
GAGTCTGTTGAAGTCGTAAAGAAAAGATGTCAAGAAATCGATTATCCCGTGTTGGAAGAA
TACGACTTTAGAAACGACCATAGAAACCCGGATTTAGATATTGATTTGAAACCTTCCACT
CAAATCAGACCCTATCAAGAAAAATCGCTGAGTAAAATGTTTGGTAATGGGCGTGCTCGT
TCAGGGATTATTGTTTTGCCATGTGGCGCAGGTAAAACTTTGGTCGGTATTACCGCAGCA
TGTACTATAAAAAAATCCGTAATTGTTTTATGTACTTCATCAGTCTCCGTCATGCAATGG
AGGCAGCAATTTTTACAATGGTGTACCTTACAACCTGAAAATTGTGCTGTTTTCACCTCT
GATAATAAGGAAATGTTCCAGACAGAATCCGGTTTGGTTGTTTCCACTTATTCAATGGTG
GCAAACACAAGAAACAGGTCTCATGATTCACAAAAAGTTATGGATTTCTTGACCGGTAGG
GAATGGGGGTTCATTATTCTTGACGAAGTTCATGTGGTGCCCGCCGCAATGTTCCGTAGG
GTGGTCTCCACCATCGCAGCACACGCCAAATTGGGACTGACCGCAACGCTGGTTAGAGAA
GATGATAAAATTGGTGATCTGAATTTTTTAATTGGTCCAAAACTTTATGAAGCAAATTGG
ATGGAATTATCCCAAAAAGGACATATTGCAAATGTCCAATGTGCAGAGGTTTGGTGTCCC
ATGACAGCAGAATTTTACCAAGAGTATTTAAGAGAAACTGCAAGGAAAAGAATGCTACTG
TATATCATGAATCCAACAAAGTTTCAGGCATGCCAATTCTTAATTCAATATCACGAAAGG
AGGGGTGATAAGATCATCGTTTTTTCAGATAATGTTTACGCCTTACAAGAATATGCTTTG
AAAATGGGAAAACCATTTATTTATGGTTCCACACCACAACAAGAGCGTATGAACATTCTG
CAAAATTTCCAGTACAATGACCAAATCAATACCATATTTCTATCAAAAGTTGGTGATACT
TCCATCGATTTACCAGAAGCTACCTGTTTAATTCAAATATCTTCGCACTATGGGTCTCGT
CGTCAAGAAGCCCAAAGATTAGGAAGAATTTTAAGAGCTAAAAGACGTAATGACGAAGGT
TTCAATGCGTTCTTTTATTCTCTGGTTTCTAAGGATACGCAAGAAATGTACTACTCAACA
AAGAGACAAGCGTTTTTGGTAGATCAAGGTTACGCATTCAAAGTCATTACACATTTACAC
GGAATGGAGAACATTCCAAATTTGGCATATGCTTCACCCAGAGAACGTAGAGAGCTATTG
CAAGAAGTATTATTGAAGAACGAAGAAGCTGCTGGTATCGAGGTCGGTGATGACGCTGAC
AATTCTGTTGGGAGAGGTTCAAATGGCCACAAAAGATTTAAATCAAAGGCCGTTAGAGGT
GAAGGTTCATTGTCTGGTCTTGCTGGCGGTGAAGATATGGCATATATGGAATACAGTACC
AATAAAAACAAAGAACTGAAGGAACATCATCCATTAATCAGAAAGATGTATTATAAGAAT
TTGAAGAAGTGA Promoter Sequence
Download FASTA
>SSL2 YIL143C
CCGAATATTTTGACCTTGTCTGTATCCAAAGTTGTATTGGCGATTAGAATCTTAGCATTT
TCAATTCTCTTGGGTTGGTTGTTACCAAATTTTTTGGCAAGAATGAAACCTTCGTCAAGG
AACGAATCTGATAGCTTTCCACCAAGAATCTTAATGATCTGAATATGTTCTAAGTTAGTG
GAGCCCTTCAATCTCAAAATAGCATTAGTTGCTAATTCTGCGAAGTGATCCTTATCCTGA
GACAAAATTTTGGAAGATAAAGTAGTCTTGGCAATATGGATCAGATCTTCACGGAACATG
GTCTTATCATGAGAGTTGTCAACAGCCGCTTTCGTTAACGCATCCAATGCGGCTGCTGAA
GCTAGTCGGTAACCTTCAATAATAGTTTGAGGGTGGATTTTGGATTGATCAATCAACTTC
TCTGCTTCTCTAAGCAACTCTGCGCTCAAAACAGTAACACTAGTGGTACCATCTCCAACT
TCGTCATCCTGCACCTTACTGATGTTCACCAACACTTTGGCTGCGGGATTATCCAGCGGA
ATTGACTTCAGAATCGTAGCACCATCGTTTGTTACCATGCAAGTGTTACTGGACGCACTT
TGCAATAATTTATCCATCCCTTTTGGGCCTAATGTGCTTTTCACCAAATCACCCACGGCA
ATGGCACCGACAAACGCCGACAAACGGGCGTTTTCCGCTCTTTCTTCTGTAACCTGGTCT
CCAAATATCTGTACACTCATCCTGAATCTTTTGAGCTTTGTACGACTGACTCTTCTTGCC
TATTTAATGGCCACCTTTCATCCTCTTTTTTATTGCTCTGCTCTTGTCTTTTAAACTCGC
CACCGCGAAGAGAAAAAAATTTCAGATCGTTAGAAACGAGGTTTTTCTTCTAAGAAGTAT
AAGGAAAAAGGTCCTTAGTAAGGATAGATAATAGTAATGATATCTACATTATTTAGTAAA
AGTAGCATCTACTGACGTTGGAATCAGTGGAAGATAAATC
Chr coordinates
Chr IX from 83041-80510
