S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition	Log2FC
Rap1p	YBL075C	PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h	N/A
		PubMed Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9	Indirect	Microarray analysis - WT vs TF Deletion	Negative	W303a	Grown in complete synthetic medium (CSM) when selection was required, or in rich medium (YPD) at 30°C. Temperature shift experiment: exponentially growing yeast cells grown in YPD (A600 = 0.8 − 1.2) at 37°C for 1 h. Transcription factor gene deletion.	-0.93255767
		PubMed Badis G et al., Molecular cell, 2008 Dec 26;32(6):878-87	Direct	ChIP	N/A	S288c	N/A	N/A
		PubMed Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47	Indirect	RNA-seq - wt vs TF overexpression	Positive	CEN.PK2-1D	YPD medium (15h) (diauxic shift)	2.26859882029329
			Indirect	RNA-seq - wt vs TF overexpression	Positive	CEN.PK2-1D	YPD medium (36h) (post-diauxic shift)	1.77203483067317
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Positive	cen.pk-2-1C	RNA extraction at 15h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	4.81854914798072
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Positive	cen.pk-2-1C	RNA extraction at 36h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	3.41535331270321