S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Rph1p	YER096W	PubMed Cipollina C et al., Microbiology (Reading, England), 2008 Jan;154(Pt 1):337-346	Indirect	Microarray analysis - WT vs TF Deletion	Negative	SLY34	Unstressed log-phase growth (control)	Grown in rich medium (YPD) at 30 °C to log phase. Transcription factor gene deletion.	-0.867761
		PubMed Liang CY et al., Molecular biology of the cell, 2013 Oct;24(20):3251-62	Indirect	Microarray analysis - wt vs TF mutant	Negative	S288c	Unstressed log-phase growth (control)	YPD 30.C	N/A
		PubMed Shu WJ et al., Nucleic acids research, 2020 Sep 4;48(15):8360-8373	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Carbon source quality/availability	Steady state carbon-limited chemostat cultures operated at a dilution rate of 0.05 per h by continuous addition of medium (feed concentration of glucose, 10 g/liter) at 30°C. pH controlled at 5, aerated with 0.5 volume of air/volume of liquid/min and with 800 rpm agitation. Transcription factor gene deletion.	-1.30058435975211
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Carbon source quality/availability	Ethanol medium - Overexpression media lacked leucine to ensure plasmid selection. The cultures grown for 70 h in ethanol medium were diluted twice with a fresh medium to ensure continuous growth.	0.611686036861934
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Unstressed log-phase growth (control)	Grown in YPD to OD600 of 0.8 at 30 ºC. Transcription factor gene deletion.	-1.30058435975211
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Nitrogen source quality/availability	Grown in YPD to OD600 of 0.8 at 30 ºC. Treated with rapamycin for 2h (100 nM). Transcription factor gene deletion.	0.611686036861934
		PubMed Fang W et al., Cell reports, 2022 Apr 12;39(2):110672	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	CEN.PK	Carbon source quality/availability	Yeast cells grown to log phase in YPL medium from 0.1 OD with switch to SL minimal medium for 1h. Transcription factor gene deletion.	-0.710384539211835
		PubMed Glazier VE et al., mBio, 2023 Oct 31;14(5):e0152123	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Unstressed log-phase growth (control)	Cultured in minimal medium (1.7 g/L YNB, 5 g/L ammonium sulfate, 20 g/L glucose, 80 mg/L histidine, 80 mg/L methionine, 80 mg/L uracil and 240 mg/L leucine) with 200 rpm orbital shaking at 30°C, pH 5.5, until the mid-exponential phase (OD600 = 0.6). Transcription factor gene deletion.	2.44219456146413