S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition	Log2FC
Rap1p	YJL026W	PubMed Lieb JD et al., Nature genetics, 2001 Aug;28(4):327-34	Direct	Chip-on-chip	N/A	S288c	N/A	N/A
		PubMed Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Grown in complete synthetic medium (CSM) when selection was required, or in rich medium (YPD) at 30°C. Temperature shift experiment: exponentially growing yeast cells grown in YPD (A600 = 0.8 − 1.2) at 37°C for 1 h. Transcription factor gene deletion.	1.10738167
		PubMed Kasahara K et al., Molecular and cellular biology, 2007 Oct;27(19):6686-705	Direct	Chip-on-chip	N/A	S288c	YPD	N/A
		PubMed Tomar RS et al., The EMBO journal, 2008 Jun 4;27(11):1575-84	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Methylmethane sulfonate stress	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	1.8007683620218
		PubMed Bondra ER et al., Proceedings of the National Academy of Sciences of the United States of America, 2023 Oct 3;120(40):e2304343120	Direct	ChIP - seq	N/A	W303	YPD medium	N/A
		PubMed Buechel ER et al., FEBS letters, 2024 Jan;598(2):169-186	Direct	ChEC-seq2	N/A	BY4741	Control	N/A
		PubMed Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47	Indirect	RNA-seq - wt vs TF overexpression	Positive	CEN.PK2-1D	YPD medium (15h) (diauxic shift)	1.76982875994948
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Positive	cen.pk-2-1C	RNA extraction at 15h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	3.41013477860819