S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition	Log2FC
Rox1p	YLR177W	PubMed Murad AM et al., Molecular microbiology, 2001 Nov;42(4):981-93	Indirect	Microarray analysis - wt vs TF mutant	Negative	JM43 / RZ53-6	Aerobiosis; cells grown in SSG-TEA (10 g/L galactose, 0.1% Tween 80, 20 mg/L ergosterol, 350 ppm silicone antifoam) or YPGalactose medium	N/A
		PubMed van der Horst SC et al., Nature communications, 2025 Feb 6;16(1):1416	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	W303	0 min: RNA-seq performed in YPAD medium. Overnight cultures were diluted in fresh YPAD and grown for 3 h. Cells were then synchronized in G1 by α-factor treatment for 2 h, washed once in YPAD, and released into YPAD containing 200 mM hydroxyurea (HU). Samples were collected at t=0min: immediately after α-factor synchronization (pre-HU release)	-0.363459
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	W303	60 min: RNA-seq performed in YPAD medium. Overnight cultures were diluted in fresh YPAD and grown for 3 h. Cells were then synchronized in G1 by α-factor treatment for 2 h, washed once in YPAD, and released into YPAD containing 200 mM hydroxyurea (HU). Samples were collected at t=60min: 60 min after release into HU (replication stress condition)	-0.291687