S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Rap1p	YLR441C	PubMed Lieb JD et al., Nature genetics, 2001 Aug;28(4):327-34	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Lee TI et al., Science (New York, N.Y.), 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303a	Stress	Exponentially growing cells (OD600= 0.8 - 1.2) grown in YPD for 1 hour at 37.C	N/A
		PubMed Kasahara K et al., Molecular and cellular biology, 2007 Oct;27(19):6686-705	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD	N/A
		PubMed Lavoie H et al., PLoS biology, 2010 Mar 9;8(3):e1000329	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	1.8358164620778
		PubMed Reja R et al., Genes & development, 2015 Sep 15;29(18):1942-54	Direct	ChIP-exo	N/A	S288c	Unstressed log-phase growth (control)	Strain was grown to OD600 0.8 at 25.C in 500 mL of YPD	N/A
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	Unstressed log-phase growth (control)	YPD medium, 25.C	N/A
		PubMed Bondra ER et al., Proceedings of the National Academy of Sciences of the United States of America, 2023 Oct 3;120(40):e2304343120	Direct	ChIP - seq	N/A	W303	Unstressed log-phase growth (control)	YPD medium	N/A
		PubMed Buechel ER et al., FEBS letters, 2024 Jan;598(2):169-186	Direct	ChEC-seq2	N/A	BY4741	Unstressed log-phase growth (control)	Control	N/A
		PubMed Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47	Indirect	RNA-seq - wt vs TF overexpression	Negative	CEN.PK2-1D	Carbon source quality/availability	YPD medium (36h) (post-diauxic shift)	-1.01722556910961
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Negative	cen.pk-2-1C	Carbon source quality/availability	RNA extraction at 36h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	-2.02402283853316