Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ATG12
Systematic Name YBR217W
Alias APG12
Strain S288c
Description Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; homolog of mammalian ULK1
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>ATG12 YBR217W
GAGTAAAATCTTCGTTCAATTGTATATCTTTTGGTGGATCAGGGGGAATATAGTTCCTGC
AGAATGTGTACACCCTACGAAGAAGGAAAAGGGCATCTTCAAAAGTGTCCGCATGACTAT
ACACAAATTTCTCAATTGTTGACACAGCAGCTCCCAGATATTTCGAAGGAAACAGAGTAG
AAATCCTTTTCAGACTCGCCCCTATGAATTCAAATAAAATGTAGGATTTCAACTTCAAGA
AAAATTCATTTGAACTCTTGCTTTCACCGTAGGATGGAAAATCTTTTCGATTAGAGGAAT
TTTCGATTACTCCTTCAGGAGGTAACGTATTGGCCTTTTTATCAACAAAGTCTTCCTTAT
TCTGTTGATCACTCTTGGAAAAATCTTTTGAACAAAGGGATGAAAGCAACTCCAACCCAG
TAATTAAACATTTTTTGGGCTCGCCTTGGATTGAGATGGCATAGAAACACTTCATTACAC
CTTGGACAATCATATTCGTACCTAGTCTTCCATTTACATCGACATTATCCTTTGACAAGA
ACTTCAATAATCCCTTAGGCAGATCCCAACCGATTTCACCAGTAGTACTCGGATTATCCT
CTAACAATGTATTCAAAGTTTCAATGAATCTCGTCTTTTCTTCATAGCTCCCCTCTTGGT
TAACTTGCTCGCCATATATATCAATCAATGTTACCAACTCAAGAAGATCCTCCTTCTGAG
TTTTGAACGCATCAGTAACCTCAAAAAGTATGTCATCAATTGGTTCCATTAGTGTCTGAG
TATCGTATTGAATGTCTAGGGTGATTTTCTTTTTCAGTGTTTATTTGTTAATAATGTTCA
CCGGCAATTAGTCTTTATTTTTTTCCTTTACATTGTCAAATTTAAAGAATCGTACTTATG
AAGGATGCCCGCTTAGTGTTTGACAGAAAGCTACTTGAGCTGAAGAAATAAACGTACATC
CCTAACTGTATATTCTACAGTAGAGTGAACCAATGACAGT
Chr coordinates Chr II from 657832-658392
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