Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ATG12
Systematic Name
YBR217W
Alias
APG12
Strain
S288c
Description
Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; homolog of mammalian ULK1
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>ATG12 YBR217W
GAGTAAAATCTTCGTTCAATTGTATATCTTTTGGTGGATCAGGGGGAATATAGTTCCTGC
AGAATGTGTACACCCTACGAAGAAGGAAAAGGGCATCTTCAAAAGTGTCCGCATGACTAT
ACACAAATTTCTCAATTGTTGACACAGCAGCTCCCAGATATTTCGAAGGAAACAGAGTAG
AAATCCTTTTCAGACTCGCCCCTATGAATTCAAATAAAATGTAGGATTTCAACTTCAAGA
AAAATTCATTTGAACTCTTGCTTTCACCGTAGGATGGAAAATCTTTTCGATTAGAGGAAT
TTTCGATTACTCCTTCAGGAGGTAACGTATTGGCCTTTTTATCAACAAAGTCTTCCTTAT
TCTGTTGATCACTCTTGGAAAAATCTTTTGAACAAAGGGATGAAAGCAACTCCAACCCAG
TAATTAAACATTTTTTGGGCTCGCCTTGGATTGAGATGGCATAGAAACACTTCATTACAC
CTTGGACAATCATATTCGTACCTAGTCTTCCATTTACATCGACATTATCCTTTGACAAGA
ACTTCAATAATCCCTTAGGCAGATCCCAACCGATTTCACCAGTAGTACTCGGATTATCCT
CTAACAATGTATTCAAAGTTTCAATGAATCTCGTCTTTTCTTCATAGCTCCCCTCTTGGT
TAACTTGCTCGCCATATATATCAATCAATGTTACCAACTCAAGAAGATCCTCCTTCTGAG
TTTTGAACGCATCAGTAACCTCAAAAAGTATGTCATCAATTGGTTCCATTAGTGTCTGAG
TATCGTATTGAATGTCTAGGGTGATTTTCTTTTTCAGTGTTTATTTGTTAATAATGTTCA
CCGGCAATTAGTCTTTATTTTTTTCCTTTACATTGTCAAATTTAAAGAATCGTACTTATG
AAGGATGCCCGCTTAGTGTTTGACAGAAAGCTACTTGAGCTGAAGAAATAAACGTACATC
CCTAACTGTATATTCTACAGTAGAGTGAACCAATGACAGT
Chr coordinates
Chr II from 657832-658392