S.cerevisiae - Yeastract

Locus Information

Standard Name	NPL3
Systematic Name	YDR432W
Alias	MTR13, MTS1, NAB1, NOP3
Strain	S288c
Description	RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>NPL3 YDR432W AATCCAAGAGATCGCCGTATCTCAAGTCTGTAATTTTCATAGGATCTCCGCCGGAGTTAT TCAGGGAAGGATAAATAGACTGTTGAAATTTACTCCAGAAATAGTAATTGGCATTTGATA TTTGACCTTTCATTTCGTTATAGACAACACCTTTGAAAACAATGTTACTCTCCGGGTCTG TGATGTTTTTATGCTCCAACCTCCAACCCTCCTGATCAAAATCTTCTTGTTTAAGTAGCG GATTCAAGGTGGAGTCTAAATAAACACCTCTTAAATTAGCGAAATCTTGAGGGTTCGTAG TGGAAAAGGGAAAAAATGTATAATCTGGACCTGTCATAGCGTTCATGAAATTAGCTAGAG ATTTATTTAGCATTTTGAAAAAAGGGTCCCTAACTGGATATTTAACAGACCCACACAACG TTGTATGCTCTAGAATATGAGGGACCCCAGTGGAATCTGGAGGGTTGGTTTTAAAAGCAA TGCTGAACACATTATTCTTGTCGTCTCTATCAATATGCAAATGCTCGGCTCCTGTCTGGG AGTGCACCAAATCTACCGCAGTGAGTCTCAGCTCCGGAACCGGTAGAATTCTTCTCACTT CATAACCATGGAATATACCTCCAACTGGATATTTTCTAACGGCCTGTGCTTGGGCATACG AGGACGCAAATCGCTGAAACCGCAACATATATACCGCAGTATATTTTATAGTAACTTTAT TCTTTTGAGTAGCCTTCTAATTGGTGGCTTATTGATTACAATTGCTTGTTATCATATCTG TCAATGCTTGTTCAACAATTCAATGATTTACTACTACCTTTATCATAGAGCCCCTCCGTA TATTTATCACTGTAAACGAAGGGCAAAATTTTTTACATTCTTTTTTTTCGCCACCCAAAG GGATTTAAAAAGGACATGAGAAAAATAATTTCCTCTCTTCTAAATATATATACTTTTGAA GGAATCAAAATTAAGCAATTACGCTAAAACCATAAGGATA
Chr coordinates	Chr IV from 1328783-1330027