Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HIS1
Systematic Name
YER055C
Strain
S288c
Description
ATP phosphoribosyltransferase; a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HIS1 YER055C
ATGGATTTGGTGAACCATCTAACCGATAGACTACTGTTTGCAATCCCAAAGAAAGGTCGT
TTATATTCTAAAAGTGTTTCTATTTTGAATGGTGCTGATATTACCTTTCACCGCTCTCAA
AGATTAGACATTGCACTAAGCACAAGCTTACCTGTAGCGTTGGTCTTTCTGCCCGCTGCA
GATATTCCAACTTTTGTTGGTGAAGGTAAATGTGATCTTGGTATAACTGGTGTTGACCAA
GTTCGTGAATCTAACGTCGACGTAGACTTAGCAATCGATTTGCAATTTGGTAACTGTAAA
TTGCAGGTACAAGTCCCCGTAAATGGCGAGTATAAAAAGCCAGAACAGTTAATTGGCAAA
ACCATTGTTACCAGTTTCGTGAAACTTGCTGAAAAATACTTTGCCGATTTGGAAGGTACT
ACTGTTGAAAAAATGACCACAAGGATAAAGTTTGTCAGTGGTTCCGTGGAGGCATCATGT
GCTCTGGGAATTGGTGATGCTATTGTAGATCTTGTAGAGAGTGGTGAGACAATGAGGGCA
GCAGGTTTAGTTGATATTGCCACCGTCCTAAGCACAAGTGCCTACCTAATAGAATCAAAG
AACCCAAAGAGCGATAAGAGTTTGATTGCTACTATCAAATCAAGAATTGAAGGTGTCATG
ACCGCTCAAAGGTTCGTTTCATGTATTTATAACGCACCTGAAGACAAGCTGCCTGAACTG
TTGAAGGTGACGCCTGGCCGTAGAGCACCAACCATTTCCAAAATTGACGATGAAGGATGG
GTTGCTGTTAGTTCCATGATTGAGAGAAAAACGAAGGGTGTTGTTTTAGATGAATTGAAA
AGACTCGGCGCATCTGATATCATGGTTTTCGAAATTTCTAATTGTCGTGTATAA
Promoter Sequence
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>HIS1 YER055C
AGAACATTTCTTCTACAGACGTTCCTTCAGTGCTTACAATATTGATGATTGGGATAATTG
GGAGCATCTACCTATCGGTATCGCAGGTACTGCTGCCTTAATTGTTGGTGCCTTCGGTGT
TGCATTGGGTATGTGTCAAACCTATTGGGTTGGTGAAATTGGCCGCTTAATTGGTAAATA
TGGTGGTGACATTGGGTTCGAGTTGGGTGCAAGTTGGGCCTTCATCATCTACAACATCTT
AAGACCTTTAGAATTAAAATACTTCGGTCGTTAGGAAGTAATGATTAGGGCGATCATTTC
CCCGTGCACATTTCACGTCATGTATCATAGATGCAATTTCATGTAAACTATTTAGACATC
TCATTTAATAAAAATAGCTACAAACTGTATTTTACAATATTAGTAACATATCAAAGATAA
TCTCTATGGTATATACAAAACTTCAAAAATGCCAAGACAATTTGCACGGCTGCGACCTAA
TTGAGACTTTGTGGCCTGCATATCAGTCTTACAATAAAAGCCAAAAAGAAAAAAAAAAAG
TAAGAATGCACAGGTGACTAGTGGTTATGTGACTATGTGAACGTAAAGAGAACGAGATGT
AACCCGGCAACCCGGCTAGAGAGGTTGTTTAGCATGCGAGGTATTAGACTCCTTGTCAAA
AAATTAATTAAAATATTTATTAGTTAATTTATTAGTTGCAAAGTCATTGATAACAGCGTG
ACTCTTCCCGGAAATTCTTTCATTTCGGCATTTCGAAGCGAGACCGCAAAACACGTGTAC
GCACGTAGCCAACGATTGAAAAAAAAAGCTTCCAAGTGAGTCACCTCTACCGTTGGAACT
TATAAAATATTTTTGCAGAATATACTCGCCTGAAAGTCCATTTATACGCAGTGAACTGCA
AGTATTTACCGTCTAAACTTTGGCATTTTACTCCTATTAACGGTTTGAATCTTTGAAAAT
AGAAAAGAAAGGATAGGTTTCTAAAAAATTCAATAGAAAA
Chr coordinates
Chr V from 265785-264892