Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RPL8A
Systematic Name
YHL033C
Alias
eL8, L4A, L8A, L8e, MAK7, rp6, YL5
Strain
S288c
Description
Ribosomal 60S subunit protein L8A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; L8 binds to Domain I of 25S and 5.8 S rRNAs; mutation results in decreased amounts of free 60S subunits; homologous to mammalian ribosomal protein L7A, no bacterial homolog; RPL8A has a paralog, RPL8B, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RPL8A YHL033C
ATGGCCCCAGGTAAGAAAGTCGCTCCAGCTCCATTCGGTGCTAAGTCAACTAAGTCTAAC
AAGACTAGAAACCCATTGACTCACTCTACTCCAAAGAACTTCGGTATTGGTCAAGCTGTC
CAACCAAAGAGAAACTTGTCCAGATACGTCAAATGGCCAGAATACGTCAGAGTGCAAAGA
CAAAAGAAGATCTTGTCCATCAGATTGAAGGTTCCTCCAACCATTGCTCAATTCCAATAC
ACTTTGGACAGAAACACCGCTGCCGAAACCTTCAAGTTGTTCAACAAGTACAGACCAGAA
ACTGCTGCTGAAAAGAAGGAAAGATTGACCAAAGAAGCTGCCGCTGTTGCTGAAGGTAAG
TCCAAGCAAGATGCTTCTCCAAAGCCATACGCTGTCAAGTACGGTTTGAACCACGTTGTT
GCCTTGATCGAAAACAAGAAGGCTAAGTTGGTTTTGATTGCTAACGATGTCGACCCAATT
GAATTGGTTGTCTTTTTGCCAGCTTTGTGTAAGAAGATGGGTGTTCCATACGCCATTGTC
AAGGGTAAGGCTAGATTGGGTACCTTGGTTAACCAAAAGACCTCTGCCGTTGCCGCTTTG
ACTGAAGTCAGAGCCGAAGACGAAGCTGCTTTGGCTAAGTTGGTTTCTACCATTGACGCT
AACTTCGCTGACAAATACGATGAAGTCAAGAAGCACTGGGGTGGTGGTATCCTTGGTAAC
AAGGCTCAAGCCAAGATGGACAAGAGAGCTAAGAACTCCGACTCCGCTTAA
Promoter Sequence
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>RPL8A YHL033C
TAGTTTTCGTCCCCGCATTTAGTGGCCTATTCGCTCCCTATTGGGACCCAGATGCCAGAG
CCACCATAATGGGGATGTCTCAATTCACTACTGCCTCCCACATCGCCAGAGCTGCCGTGG
AAGGTGTTTGCTTTCAAGCCAGGGCTATCTTGAAGGCAATGAGTTCTGACGCGTTTGGTG
AAGGTTCCAAAGACAGGGACTTTTTAGAGGAAATTTCCGACGTCACATATGAAAAGTCGC
CCCTGTCGGTTCTGGCAGTGGATGGCGGGATGTCGAGGTCTAATGAAGTCATGCAAATTC
AAGCCGATATCTTAGGTCCCTGTGTCAAAGTCAGAAGGTCTCCGACAGCGGAATGTACCG
CATTGGGGGCAGCCATTGCAGCCAATATGGCTTTCAAGGATGTGAACGAGCGCCCATTAT
GGAAGGACCTACACGATGTTAAGAAATGGGTCTTTTACAATGGAATGGAGAAAAACGAAC
AAATATCACCAGAGGCTCATCCAAACCTTAAGATATTCAGAAGTGAATCCGACGATGCTG
AAAGGAGAAAGCATTGGAAGTATTGGGAAGTTGCCGTGGAAAGATCCAAAGGTTGGCTGA
AGGACATAGAAGGTGAACACGAACAGGTTCTAGAAAACTTCCAATAACAACATAAATAAT
TTCTATTAACAATGTAATTTCCATAATTTTATATTCCTCTCCACCTTCTATTGCATCATG
TACTATTCAAATGACTGTAACACTAGTATTATGAAGAAAACACCCAAACATATCTAGGCC
ATCAGATTTTTTTTTTTTCATTTTTCATTTTTTTCTCATTTTCTTATTTATTTTTATTGA
AAAATAATAACCGACGCAAACAAATTGGAAAAACCAACGCAAAAAAAAAAAGACGCTAAA
TTGTTTATAAAGGCGAGGAATTTGTATCTATCAATTACTATTCCAGTTGTCAGTTTACAT
TGCTTACCCTCTATTATCACATCAAAACAACTAATTCGAA
Chr coordinates
Chr VIII from 36025-35255