Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SRV2
Systematic Name YNL138W
Alias CAP
Strain S288c
Description CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>SRV2 YNL138W
TGCGAATATGTATCAACTGAAACCGTTTCACCCTATTATGCTTTAGATAAAGACGATAAA
ATCACAGCCCTATAATTTATGCAACAGTGTTTGCTTCTAAATCAACGTGTTCCCTGGGCA
TAAACTCTCATACGTTATGTCGCTATTGAAGAAATAGCGGAAAATCTTACGCCGAAGTTA
GCGTTGTCACCCGGGAAGAAGAGAAGAACATAAGCCTTCTCATTCAGAACATGTAAATAG
TGGCTAAAATGGTTATATTACACAATTCGAAACAGTGAAATTAAGAAAAGAAATGGTATG
TTACGTTCTATTGCGCTTTAGTTTGAATTGAAATCATCTTTACCATGGTACTAACTACGC
TTGCGATGAATCGTGCAAGTCCGTGCGGCTTATACGTAATGCTAATACTCAAAACAGGCG
GAAAAGCAGAGGCAGTTGAAGTTGCAGAAGATATACAAACAAAAGTACATCGGACTGGGA
GATGAGAGCACTACACGAGAACAGTGGCAGAGAAATGTGAGAAACGATACACTAAATACA
TTACAAGGCCACTCCGCATCTTTGGAGTACGTTTCATTGAGCCGAGGAGACCTTAGTATA
CGTGACACTCGTATTCACCTCCTGAAATCCATGTCCCCTGGCTATAAAGCCTACTTACGA
GAAGAGAGGTAGGACGTTGAAGCCACATCCATAAATAATTTTTACATAAAATTACGCCTC
GTATGTCGTTCTCAAGATTTATGGTAGAGATCACACTCAGTCAGTAACCTTTTAGGCATT
GATTCTAGTAACTGTCGAACATTATTAACCTTGATGTTTATATAAAGATATAAAATGTTG
GGACAGTATACAATTCATATCGTTTAAAATGATCTATACATGTCGCGTGAAGTCATAAAC
AGGGATTTAGAAGTGAAATCTTTTGGTAGTATAGGGGAAAACTCAGCTTGAAACTTTTCG
TAATTGAGTAGGCCAAGTTGCAACCGTGTGAAATCGAATC
Chr coordinates Chr XIV from 366741-368321
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