Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SRV2
Systematic Name
YNL138W
Alias
CAP
Strain
S288c
Description
CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SRV2 YNL138W
ATGCCTGACTCTAAGTACACAATGCAAGGTTATAACCTTGTTAAGCTATTAAAAAGGCTA
GAAGAAGCCACTGCAAGATTAGAGGATGTCACCATCTATCAAGAAGGTTATATTCAGAAT
AAATTGGAGGCATCTAAAAATAACAAGCCTTCCGACTCCGGGGCCGATGCGAATACTACG
AATGAACCTTCTGCAGAAAATGCTCCTGAAGTAGAACAAGATCCGAAATGCATAACTGCG
TTCCAATCTTACATCGGTGAGAATATTGATCCGCTGGTAGAATTATCAGGAAAGATCGAC
ACGGTGGTCTTAGATGCTTTGCAGTTGCTAAAGGGAGGCTTTCAATCGCAATTGACTTTT
TTAAGAGCTGCTGTGAGATCAAGAAAACCGGATTATTCTTCTCAAACTTTCGCTGATTCT
TTAAGACCTATCAACGAAAATATTATAAAGCTGGGTCAATTGAAGGAATCAAACCGTCAA
AGCAAATACTTCGCATATTTGAGCGCTTTATCTGAGGGTGCTCCTTTGTTCTCCTGGGTT
GCAGTGGACACTCCCGTGTCTATGGTCACAGATTTCAAGGACGCAGCACAGTTTTGGACT
AATAGAATTTTGAAAGAATACAGAGAGTCTGATCCTAATGCTGTTGAATGGGTTAAGAAA
TTTTTGGCCTCTTTCGATAATTTGAAAGCCTACATTAAAGAGTATCATACTACTGGGGTT
TCCTGGAAAAAAGACGGTATGGATTTTGCTGACGCGATGGCACAATCAACGAAGAATACA
GGTGCTACTTCATCTCCTTCGCCAGCAAGTGCTACAGCGGCTCCAGCACCACCACCTCCT
CCACCAGCCCCACCAGCTTCCGTCTTTGAAATCTCTAATGATACACCAGCAACGAGTAGT
GATGCTAACAAAGGCGGTATTGGCGCGGTCTTCGCCGAACTAAATCAGGGTGAAAATATC
ACTAAGGGTTTGAAAAAAGTAGACAAATCCCAACAAACTCACAAAAATCCTGAATTACGT
CAATCCTCTACAGTTTCTTCCACAGGAAGTAAATCCGGTCCACCACCAAGGCCAAAAAAG
CCATCAACATTGAAAACTAAGAGGCCTCCTAGAAAGGAATTGGTAGGAAACAAATGGTTT
ATTGAGAATTACGAAAATGAAACTGAATCTCTGGTTATTGATGCAAATAAAGATGAGTCT
ATCTTCATAGGTAAATGTTCTCAAGTTCTTGTTCAAATAAAAGGAAAAGTTAACGCTATC
TCGTTGAGTGAAACTGAGTCATGCAGTGTTGTTCTTGATTCTAGCATTTCCGGTATGGAT
GTCATCAAATCCAACAAGTTTGGCATTCAAGTTAACCATTCCCTACCTCAAATCTCCATT
GATAAATCTGACGGCGGTAACATCTATTTATCCAAGGAATCCTTGAATACTGAAATCTAC
ACCTCGTGCTCAACTGCTATTAACGTCAACTTACCAATCGGCGAGGACGATGATTACGTA
GAATTCCCAATCCCTGAACAGATGAAGCATAGCTTCGCTGATGGTAAGTTCAAATCTGCT
GTTTTCGAACATGCTGGTTAA
Promoter Sequence
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>SRV2 YNL138W
TGCGAATATGTATCAACTGAAACCGTTTCACCCTATTATGCTTTAGATAAAGACGATAAA
ATCACAGCCCTATAATTTATGCAACAGTGTTTGCTTCTAAATCAACGTGTTCCCTGGGCA
TAAACTCTCATACGTTATGTCGCTATTGAAGAAATAGCGGAAAATCTTACGCCGAAGTTA
GCGTTGTCACCCGGGAAGAAGAGAAGAACATAAGCCTTCTCATTCAGAACATGTAAATAG
TGGCTAAAATGGTTATATTACACAATTCGAAACAGTGAAATTAAGAAAAGAAATGGTATG
TTACGTTCTATTGCGCTTTAGTTTGAATTGAAATCATCTTTACCATGGTACTAACTACGC
TTGCGATGAATCGTGCAAGTCCGTGCGGCTTATACGTAATGCTAATACTCAAAACAGGCG
GAAAAGCAGAGGCAGTTGAAGTTGCAGAAGATATACAAACAAAAGTACATCGGACTGGGA
GATGAGAGCACTACACGAGAACAGTGGCAGAGAAATGTGAGAAACGATACACTAAATACA
TTACAAGGCCACTCCGCATCTTTGGAGTACGTTTCATTGAGCCGAGGAGACCTTAGTATA
CGTGACACTCGTATTCACCTCCTGAAATCCATGTCCCCTGGCTATAAAGCCTACTTACGA
GAAGAGAGGTAGGACGTTGAAGCCACATCCATAAATAATTTTTACATAAAATTACGCCTC
GTATGTCGTTCTCAAGATTTATGGTAGAGATCACACTCAGTCAGTAACCTTTTAGGCATT
GATTCTAGTAACTGTCGAACATTATTAACCTTGATGTTTATATAAAGATATAAAATGTTG
GGACAGTATACAATTCATATCGTTTAAAATGATCTATACATGTCGCGTGAAGTCATAAAC
AGGGATTTAGAAGTGAAATCTTTTGGTAGTATAGGGGAAAACTCAGCTTGAAACTTTTCG
TAATTGAGTAGGCCAAGTTGCAACCGTGTGAAATCGAATC
Chr coordinates
Chr XIV from 366741-368321