C.albicans - PathoYeastract

Genome Scale Metabolic model

Genome Scale Metabolic model
Name	iRV781
URL	https://www.mdpi.com/2309-608X/6/3/171#supplementary
Associated publication
Title	Genome-Scale Metabolic Model of the Human Pathogen Candida albicans: A Promising Platform for Drug Target Prediction.
Journal	J Fungi (Basel)
Authors	Viana R, Dias O, Lagoa D, Galocha M, Rocha I, Teixeira MC
Date	2020 Sep 11
Pubmed	https://pubmed.ncbi.nlm.nih.gov/32932905/

Available media

Detailed description of each indicated media: "Synthetic Minimal medium" includes glucose and ammonia as sources of carbon and nitrogen, respectively, other essential elements and high oxygen availability; "Glucose-rich SC medium", SC standing for Synthetic Complete, includes glucose and ammonia as sources of carbon and nitrogen, respectively, all amino acids, other essential elements and low oxygen availability; RPMI stands for Roswell Park Memorial Institute 1640 medium, designed to mimic human serum composition. For each metabolite that could be added to the simulated growth medium, an exchange reaction code and name is provided, followed by the rate of metabolite uptake into the cell.
Note: The YEASTRACT+ team is available to include additional media options upon request by the users.

Reaction	Name	Uptake rate
Reaction	Name	Synthetic Minimal medium	RPMI 1640 medium
EX_C02341__extr	trans-Aconitate =>	0.000	0.000
EX_C00865__extr	Phospholipid =>	0.000	0.000
EX_C00061__extr	FMN =>	0.000	0.000
EX_C00299__extr	Uridine =>	0.000	0.000
EX_C00860__extr	L-Histidinol =>	0.000	0.000
EX_C00750__extr	Spermine =>	0.000	0.000
EX_C00079__extr	L-Phenylalanine =>	0.000	-1000.000
EX_E_biomass__cyto	e-Biomass =>	0.000	0.000
EX_C00243__extr	Lactose =>	0.000	0.000
EX_C00361__extr	dGDP =>	0.000	0.000
EX_C01724__extr	Lanosterol =>	0.000	0.000
EX_C00379__extr	Xylitol =>	0.000	0.000
EX_C00074__extr	Phosphoenolpyruvate =>	0.000	0.000
EX_C00082__extr	L-Tyrosine =>	0.000	-1000.000
EX_C00192__extr	Hydroxylamine =>	0.000	0.000
EX_C00002__extr	ATP =>	0.000	0.000
EX_C00104__extr	IDP =>	0.000	0.000
EX_C00163__extr	Propanoate =>	0.000	0.000
EX_C00792__extr	D-Arginine =>	0.000	0.000
EX_C00492__extr	Raffinose =>	0.000	0.000
EX_C00134__extr	Putrescine =>	0.000	0.000
EX_C00010__extr	CoA =>	0.000	0.000
EX_C00159__extr	D-Mannose =>	0.000	0.000
EX_C00121__extr	D-Ribose =>	0.000	0.000
EX_C00008__extr	ADP =>	0.000	0.000
EX_C04525__extr	Fecosterol =>	0.000	0.000
EX_C00120__extr	Biotin <=>	-1000.000	-1000.000
EX_C00049__extr	L-Aspartate =>	0.000	-1000.000
EX_C05361__extr	Hydrazine =>	0.000	0.000
EX_C00016__extr	FAD =>	0.000	0.000
EX_C00003__extr	NAD+ =>	0.000	0.000
EX_C00218__extr	Methylamine =>	0.000	0.000
EX_C00015__extr	UDP =>	0.000	0.000
EX_C00438__extr	N-Carbamoyl-L-aspartate =>	0.000	0.000
EX_C14819__extr	Fe3+ =>	0.000	0.000
EX_C00329__extr	D-Glucosamine =>	0.000	0.000
EX_C00286__extr	dGTP =>	0.000	0.000
EX_C00011__extr	CO2 <=>	-1000.000	-1000.000
EX_C00062__extr	L-Arginine =>	0.000	-1000.000
EX_C00065__extr	L-Serine =>	0.000	-1000.000
EX_C00180__extr	Benzoate =>	0.000	0.000
EX_C00059__extr	Sulfate <=>	-1000.000	-1000.000
EX_C01589__extr	Imidazole =>	0.000	0.000
EX_C00007__extr	Oxygen <=>	-1000.000	-1000.000
EX_C05684__extr	Selenite =>	0.000	0.000
EX_C06473__extr	2-Keto-D-gluconic acid =>	0.000	0.000
EX_C00191__extr	D-Glucuronate =>	0.000	0.000
EX_C00033__extr	Acetate =>	0.000	0.000
EX_C00116__extr	Glycerol =>	0.000	0.000
EX_C00534__extr	Pyridoxamine =>	0.000	0.000
EX_C00086__extr	Urea =>	0.000	0.000
EX_C00360__extr	dAMP =>	0.000	0.000
EX_C00148__extr	L-Proline =>	0.000	-1000.000
EX_C00333__extr	D-Galacturonate =>	0.000	0.000
EX_C00515__extr	D-Ornithine =>	0.000	0.000
EX_C00250__extr	Pyridoxal =>	0.000	0.000
EX_C01092__extr	8-Amino-7-oxononanoate =>	0.000	0.000
EX_C00031__extr	D-Glucose <=>	-7.560	-7.560
EX_C00346__extr	Ethanolamine phosphate =>	0.000	0.000
EX_C00054__extr	Adenosine 3\\',5\\'-bisphosphate =>	0.000	0.000
EX_C00017__extr	Protein =>	0.000	0.000
EX_C00140__extr	N-Acetyl-D-glucosamine =>	0.000	0.000
EX_C00019__extr	S-Adenosyl-L-methionine =>	0.000	0.000
EX_C00081__extr	ITP =>	0.000	0.000
EX_C00001__extr	H2O <=>	-1000.000	-1000.000
EX_C00568__extr	4-Aminobenzoate =>	0.000	-1000.000
EX_C00052__extr	UDP-alpha-D-galactose =>	0.000	0.000
EX_C00162__extr	Fatty acid =>	0.000	0.000
EX_C00473__extr	Retinol =>	0.000	0.000
EX_C00257__extr	D-Gluconic acid =>	0.000	0.000
EX_C00089__extr	Sucrose =>	0.000	0.000
EX_C06254__extr	Lysophospholipid =>	0.000	0.000
EX_C00315__extr	Spermidine =>	0.000	0.000
EX_C00147__extr	Adenine =>	0.000	0.000
EX_C05980__extr	Cardiolipin =>	0.000	0.000
EX_C05437__extr	Zymosterol =>	0.000	0.000
EX_C06424__extr	Tetradecanoic acid =>	0.000	0.000
EX_C01684__extr	Ergosterol =>	0.000	0.000
EX_C00362__extr	dGMP =>	0.000	0.000
EX_C00253__extr	Nicotinate =>	0.000	0.000
EX_C00198__extr	D-Glucono-1,5-lactone =>	0.000	0.000
EX_C00532__extr	L-Arabitol =>	0.000	0.000
EX_C00311__extr	Isocitrate =>	0.000	0.000
EX_C00256__extr	(R)-Lactate =>	0.000	0.000
EX_C00366__extr	Urate =>	0.000	0.000
EX_C00864__extr	Pantothenate =>	0.000	-1000.000
EX_C00751__extr	Squalene =>	0.000	0.000
EX_C00037__extr	Glycine =>	0.000	-1000.000
EX_C00255__extr	Riboflavin =>	0.000	-1000.000
EX_C00035__extr	GDP =>	0.000	0.000
EX_C00314__extr	Pyridoxine =>	0.000	-1000.000
EX_C00036__extr	Oxaloacetate =>	0.000	0.000
EX_C00088__extr	Nitrite =>	0.000	0.000
EX_C00642__extr	4-Hydroxyphenylacetate =>	0.000	0.000
EX_C00474__extr	Ribitol =>	0.000	0.000
EX_Histidine_Residue__extr	Histidine Residue =>	0.000	0.000
EX_C07086__extr	Phenylacetic acid =>	0.000	0.000
EX_C00080__extr	H+ <=>	-1000.000	-1000.000
EX_C00149__extr	(S)-Malate =>	0.000	0.000
EX_C05402__extr	Melibiose =>	0.000	0.000
EX_C01083__extr	alpha,alpha-Trehalose =>	0.000	0.000
EX_C00546__extr	Methylglyoxal =>	0.000	0.000
EX_C00144__extr	GMP =>	0.000	0.000
EX_C00262__extr	Hypoxanthine =>	0.000	0.000
EX_C00380__extr	Cytosine =>	0.000	0.000
EX_C00259__extr	L-Arabinose =>	0.000	0.000
EX_C00026__extr	2-Oxoglutarate =>	0.000	0.000
EX_C00021__extr	S-Adenosyl-L-homocysteine =>	0.000	0.000
EX_C00385__extr	Xanthine =>	0.000	0.000
EX_C00407__extr	L-Isoleucine =>	0.000	-1000.000
EX_C07649__extr	5-FU =>	0.000	0.000
EX_C00487__extr	Carnitine =>	0.000	0.000
EX_C00369__extr	Starch =>	0.000	0.000
EX_C00208__extr	Maltose =>	0.000	0.000
EX_C00300__extr	Creatine =>	0.000	0.000
EX_C00077__extr	L-Ornithine =>	0.000	0.000
EX_C00157__extr	Phosphatidylcholine =>	0.000	0.000
EX_C00956__extr	L-2-Aminoadipate =>	0.000	0.000
EX_C15777__extr	Episterol =>	0.000	0.000
EX_C00216__extr	D-Arabinose =>	0.000	0.000
EX_C00186__extr	(S)-Lactate =>	0.000	0.000
EX_C15587__extr	Purine =>	0.000	0.000
EX_C00047__extr	L-Lysine =>	0.000	-1000.000
EX_C14818__extr	Fe2+ =>	0.000	0.000
EX_C00181__extr	D-Xylose =>	0.000	0.000
EX_C00106__extr	Uracil =>	0.000	0.000
EX_C00499__extr	Allantoate =>	0.000	0.000
EX_C00503__extr	Erythritol =>	0.000	0.000
EX_C00022__extr	Pyruvate =>	0.000	0.000
EX_C00009__extr	Orthophosphate <=>	-1000.000	-1000.000
EX_C00114__extr	Choline =>	0.000	-1000.000
EX_C00327__extr	L-Citrulline =>	0.000	0.000
EX_Pyridoxal_phosphate_Residue__extr	Pyridoxal phosphate Residue =>	0.000	0.000
EX_C00334__extr	4-Aminobutanoate =>	0.000	0.000
EX_C02843__extr	Long-chain acyl-CoA =>	0.000	0.000
EX_C00350__extr	Phosphatidylethanolamine =>	0.000	0.000
EX_C02571__extr	O-Acetylcarnitine =>	0.000	0.000
EX_C00014__extr	Ammonia <=>	-1000.000	-1000.000
EX_C00012__extr	Peptide =>	0.000	0.000
EX_C01697__extr	Galactitol =>	0.000	0.000
EX_C00123__extr	L-Leucine =>	0.000	-1000.000
EX_C00504__extr	Folate =>	0.000	-1000.000
EX_C03172__extr	S-Methyl-L-methionine =>	0.000	0.000
EX_C00064__extr	L-Glutamine =>	0.000	-1000.000
EX_C02737__extr	Phosphatidylserine =>	0.000	0.000
EX_C00122__extr	Fumarate =>	0.000	0.000
EX_C00060__extr	Carboxylate =>	0.000	0.000
EX_C00020__extr	AMP =>	0.000	0.000
EX_C00247__extr	L-Sorbose =>	0.000	0.000
EX_C00073__extr	L-Methionine =>	0.000	-1000.000
EX_C00392__extr	Mannitol =>	0.000	0.000
EX_C00025__extr	L-Glutamate =>	0.000	-1000.000
EX_C00448__extr	trans,trans-Farnesyl diphosphate =>	0.000	0.000
EX_C00242__extr	Guanine =>	0.000	0.000
EX_C00378__extr	Thiamine =>	0.000	-1000.000
EX_C00430__extr	5-Aminolevulinate =>	0.000	0.000
EX_C00137__extr	myo-Inositol =>	0.000	-1000.000
EX_C00183__extr	L-Valine =>	0.000	-1000.000
EX_C00078__extr	L-Tryptophan =>	0.000	-1000.000
EX_C00507__extr	L-Rhamnose =>	0.000	0.000
EX_C06186__extr	Arbutin =>	0.000	0.000
EX_C00185__extr	Cellobiose =>	0.000	0.000
EX_C00791__extr	Creatinine =>	0.000	0.000
EX_C00794__extr	D-Sorbitol =>	0.000	0.000
EX_C00188__extr	L-Threonine =>	0.000	-1000.000
EX_C00266__extr	Glycolaldehyde =>	0.000	0.000
EX_C00158__extr	Citrate =>	0.000	0.000
EX_C00135__extr	L-Histidine =>	0.000	-1000.000
EX_C00097__extr	L-Cysteine =>	0.000	-1000.000
EX_C00244__extr	Nitrate =>	0.000	-1000.000
EX_C00105__extr	UMP =>	0.000	0.000
EX_C00215__extr	Nucleotide =>	0.000	0.000
EX_C00302__extr	Glutamate =>	0.000	0.000
EX_C00322__extr	2-Oxoadipate =>	0.000	0.000
EX_C00043__extr	UDP-N-acetyl-alpha-D-glucosamine =>	0.000	0.000
EX_C00712__extr	(9Z)-Octadecenoic acid =>	0.000	0.000
EX_C01451__extr	Salicin =>	0.000	0.000
EX_C00187__extr	Cholesterol =>	0.000	0.000
EX_C00095__extr	D-Fructose =>	0.000	0.000
EX_C00153__extr	Nicotinamide =>	0.000	-1000.000
EX_C00096__extr	GDP-mannose =>	0.000	0.000
EX_C00044__extr	GTP =>	0.000	0.000
EX_C01672__extr	Cadaverine =>	0.000	0.000
EX_C01898__extr	Cellodextrin =>	0.000	0.000
EX_C00525__extr	D-Tryptophan =>	0.000	0.000
EX_C00417__extr	cis-Aconitate =>	0.000	0.000
EX_C00263__extr	L-Homoserine =>	0.000	0.000
EX_C00797__extr	Ethylamine =>	0.000	0.000
EX_C00094__extr	Sulfite =>	0.000	0.000
EX_C00042__extr	Succinate =>	0.000	0.000
EX_C00152__extr	L-Asparagine =>	0.000	-1000.000
EX_C00320__extr	Thiosulfate =>	0.000	0.000
EX_C03150__extr	Nicotinamide-beta-riboside =>	0.000	0.000
EX_C00029__extr	UDP-glucose =>	0.000	0.000
EX_C00249__extr	Hexadecanoic acid =>	0.000	0.000
EX_C00469__extr	Ethanol =>	0.000	0.000
EX_C00041__extr	L-Alanine =>	0.000	0.000
EX_C00370__extr	Sterol =>	0.000	0.000