C.albicans - PathoYeastract

Regulation Reference(s)

The PathoYeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Tac1p	C3_05220W_A	PubMed Coste AT et al., Eukaryot Cell, 2004 Dec;3(6):1639-52	Direct	EMSA	N/A	SC5314	Control
			Indirect	Northern blot - wt vs TF mutant	Positive	SC5314	Fluphenazine
			Indirect	lacZ - wt vs TF mutant	Positive	SC5314	Fluphenazine
			Indirect	Microarray analysis - wt vs TF mutant	Positive	SC5314	Control
		PubMed Cost et al., Eukaryot Cell, 2007;6(10):1889-1904	Indirect	Western blot - wt vs TF mutant	Positive	SC5314	Fluphenazine
		PubMed Znaidi S et al., Mol Microbiol, 2007 Oct;66(2):440-52	Indirect	Northern blot - wt vs TF mutant	Positive	SC5314	Control
		PubMed Liu TT et al., Eukaryot Cell, 2007 Nov;6(11):2122-38	Direct	Chip-on-chip	N/A	SC5314	Control
		PubMed MacCallum DM et al., Antimicrob Agents Chemother, 2010 Apr;54(4):1476-83	Indirect	Northern blot - wt vs TF mutant	Positive	SC5314	Control
		PubMed Liu Z et al., Antimicrob Agents Chemother, 2017 Nov;61(11):	Direct	ChIP	N/A	SC5314	YPD
			Direct	ChIP	N/A	SC5314	10 mg/L fluphenazine during 15 min
			Direct	ChIP	N/A	SC5314	Fluphenazine stress during 30 min
			Direct	ChIP	N/A	SC5314	Fluphenazine stress during 60 min
			Direct	ChIP	Positive	SC5314	Control, YPD, 30.C
			Direct	ChIP	Positive	SC5314	Fluphenazinee stress (10 microg/mL for 15 min)
			Direct	RT-PCR - wt vs mutant promoter sequence	Positive	SC5314	10 mg/L fluphenazine
			Indirect	RT-PCR - wt vs TF mutant	Positive	SC5314	YPD
			Indirect	RT-PCR - wt vs TF mutant	Positive	SC5314	20 mg/L fluphenazine during 30 min
			Indirect	RT-PCR - wt vs TF mutant	Positive	SC5314	Fluphenazine stress
			Indirect	RT-PCR - wt vs TF mutant	Positive	SC5314	Control, YPD, 30.C
			Indirect	RT-PCR - wt vs TF mutant	Positive	SC5314	Fluphenazinee stress (20 microg/mL for 30 min)
			Indirect	Western blot - wt vs TF mutant	Positive	SC5314	YPD
			Indirect	Western blot - wt vs TF mutant	Positive	SC5314	20 mg/L fluphenazine during 30 min
			Indirect	Western blot - wt vs TF mutant	Positive	SC5314	Control, YPD, 30.C
			Indirect	Western blot - wt vs TF mutant	Positive	SC5314	Fluphenazinee stress (20 microg/mL for 30 min)
			Indirect	RT-PCR - wt vs TF overexpression	Positive	SC5314	YPD
		PubMed Liu Z et al., Antimicrob Agents Chemother, 2018 Nov;62(11):	Direct	ChIP	N/A	SN152	Farnesol stess (50 microM)
			Indirect	RT-PCR - wt vs TF mutant	Positive	SN152	1-Dodecanol stress (50 microM)
			Indirect	RT-PCR - wt vs TF mutant	Positive	SN152	Farnesol stess (50 microM)
			Indirect	RT-PCR - wt vs TF mutant	Positive	SN152	Fluphenazinee stress (25 microM)
			Indirect	Western blot - wt vs TF mutant	Positive	SN152	Farnesol stess (50 microM)
			Indirect	Western blot - wt vs TF mutant	Positive	SN152	Fluphenazinee stress (25 microM)
		PubMed Rastogi SK et al., Cell Microbiol, 2020 Feb;22(2):e13140	Indirect	RT-PCR - wt vs TF mutant	Positive	Unspecified	Control, YPD, 30.C
			Indirect	RT-PCR - wt vs TF mutant	Positive	Unspecified	20 ug/mL fluphenazine for 30 min
		PubMed Liu JY et al., Braz J Microbiol, 2020 Dec;51(4):1553-1561	Indirect	RT-PCR - wt vs TF mutant	Positive	SN152	Control, YPD, 30.C
			Indirect	Western blot - wt vs TF mutant	Positive	SN152	Control, YPD, 30.C
			Indirect	Western blot - wt vs TF mutant	Positive	SN152	Fluphenazine stress (10 mg/L for 6h)